LYVE1 Monoclonal Antibody [P4G1AT] (CPAB0128)
![LYVE1 Monoclonal Antibody [P4G1AT] (CPAB0128)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58354/63536/lyve1-monoclonal-antibody-p4g1at-cpab0128__77244__44532.1706534982.jpg?c=1 "LYVE1 Monoclonal Antibody [P4G1AT] (CPAB0128)")
- SKU:
- CPAB0128
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- P4G1AT
- Applications:
- WB
- Applications:
- ELISA
![LYVE1 Monoclonal Antibody [P4G1AT] (CPAB0128)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58354/63536/lyve1-monoclonal-antibody-p4g1at-cpab0128__77244__44532.1706534982.jpg?c=1&imbypass=on "LYVE1 Monoclonal Antibody [P4G1AT] (CPAB0128)")
Description
system_update_alt Datasheet
| Product Name: | LYVE1 Antibody |
| Product Sku: | CPAB0128 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human LYVE1 mAb is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human LYVE1 amino acids 25-235 purified from Ecoli. |
| Clone: | P4G1AT. |
| Reactivity: | Human |
| Applications: | Western Blot, ELISA |
| Purification Method: | LYVE1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG2b |
| Background: | LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves. |
| Synonyms: | Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor, LYVE-1, Cell surface retention sequence-binding protein 1, CRSBP-1, Hyaluronic acid receptor, Extracellular link domain-containing protein. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
Related Products
Lyve1 Polyclonal Antibody
OverviewProduct Name:Lyve1 Polyclonal AntibodyProduct Code:CAB23673Reactivity:Mouse, RatApplications:Western blotting
IκBα Monoclonal Antibody
OverviewProduct Name:IκBα Monoclonal AntibodyProduct Code:CAB24909Reactivity:Human, Mouse, RatApplications:Western blotting, Immu
Chk1 Monoclonal Antibody
OverviewProduct Name:Chk1 Monoclonal AntibodyProduct Code:CAB22055Reactivity:HumanApplications:Western blotting