Description
| Product Name: | LYRIC/AEG1 Monoclonal Antibody |
| Product Code: | CAB23911 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC62211 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | IHC-P, ELISA |
| Key Applications: | Immunohistochemistry |
| Recommended Dilution: | IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Cellular Location: | Cell junction, Cytoplasm, Endoplasmic reticulum membrane, Nucleus, Nucleus membrane, Single-pass membrane protein, nucleolus, perinuclear region, tight junction |
Enables NF-kappaB binding activity; double-stranded RNA binding activity; and transcription coactivator activity. Involved in several processes, including lipopolysaccharide-mediated signaling pathway; positive regulation of intracellular signal transduction; and regulation of transcription, DNA-templated. Located in endoplasmic reticulum; nuclear lumen; and perinuclear region of cytoplasm. Implicated in hepatocellular carcinoma.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 308-407 of human LYRIC/AEG1 (NP_848927.2). |
| Sequence: | SPASA GKRKT EPSAW SQDTG DANTN GKDWG RSWSD RSIFS GIGST AEPVS QSTTS DYQWD VSRNQ PYIDD EWSGL NGLSS ADPNS DWNAP AEEWG NWVDE |
| Synonyms: | 3D3, AEG1, AEG-1, LYRIC, LYRIC/3D3 |
| Calculated MW: | 64kDa |
| Observed MW: | Refer to figures |