LYL1 Antibody (PACO04257)
- SKU:
- PACO04257
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | LYL1 Antibody |
| Antibody SKU: | PACO04257 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | IHC:1:100-1:300 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from the Internal region of human Lyl-1. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | LYL1; BHLHA18; Protein lyl-1; Class A basic helix-loop-helix protein 18; bHLHa18; Lymphoblastic leukemia-derived sequence 1 |
| UniProt Protein Function: | LYL1: A chromosomal aberration involving LYL1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(7;19)(q35;p13) with TCRB.Protein type: Transcription factor; DNA-binding; OncoproteinChromosomal Location of Human Ortholog: 19p13.2Cellular Component: nucleusMolecular Function: DNA binding; protein bindingBiological Process: B cell differentiation; blood vessel maturation; positive regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent |
| UniProt Protein Details: | |
| NCBI Summary: | This gene represents a basic helix-loop-helix transcription factor. The encoded protein may play roles in blood vessel maturation and hematopoeisis. A translocation between this locus and the T cell receptor beta locus (GeneID 6957) on chromosome 7 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Sep 2010] |
| UniProt Code: | P12980 |
| NCBI GenInfo Identifier: | 226694149 |
| NCBI Gene ID: | 4066 |
| NCBI Accession: | P12980.3 |
| UniProt Secondary Accession: | P12980,O76102 |
| UniProt Related Accession: | P12980 |
| Molecular Weight: | 29,938 Da |
| NCBI Full Name: | Protein lyl-1 |
| NCBI Synonym Full Names: | LYL1, basic helix-loop-helix family member |
| NCBI Official Symbol: | LYL1 |
| NCBI Official Synonym Symbols: | bHLHa18 |
| NCBI Protein Information: | protein lyl-1 |
| UniProt Protein Name: | Protein lyl-1 |
| UniProt Synonym Protein Names: | Class A basic helix-loop-helix protein 18; bHLHa18; Lymphoblastic leukemia-derived sequence 1 |
| Protein Family: | Protein |
| UniProt Gene Name: | LYL1 |
| UniProt Entry Name: | LYL1_HUMAN |
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