Description
| Antibody Name: | Ltbp1 Antibody (PACO50750) |
| Antibody SKU: | PACO50750 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Latent-transforming growth factor beta-binding protein 1 protein (20-299AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM). |
| Synonyms: | Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1), Ltbp1 |
| UniProt Protein Function: | LTBP1: May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM). Belongs to the LTBP family. 5 isoforms of the human protein are produced by alternative splicing.Protein type: Chaperone; Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 17|17 E2Cellular Component: cell soma; cytoplasm; dendrite; extracellular matrix; extracellular region; extracellular space; microfibril; mitochondrion; perinuclear region of cytoplasm; protein complex; proteinaceous extracellular matrixMolecular Function: calcium ion binding; growth factor binding; microfibril binding; transforming growth factor beta bindingBiological Process: positive regulation of collagen biosynthetic process; transforming growth factor beta receptor signaling pathway |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8CG19 |
| NCBI GenInfo Identifier: | 1063759631 |
| NCBI Gene ID: | 268977 |
| NCBI Accession: | NP_001318166.1 |
| UniProt Secondary Accession: | Q8CG19,O88349, Q505C9, Q8BNW7, Q8C7F5, Q8CG18, Q8CIR0 B1B1D9, B1B1E1 |
| UniProt Related Accession: | Q8CG19 |
| Molecular Weight: | |
| NCBI Full Name: | latent-transforming growth factor beta-binding protein 1 isoform 7 |
| NCBI Synonym Full Names: | latent transforming growth factor beta binding protein 1 |
| NCBI Official Symbol: | Ltbp1 |
| NCBI Official Synonym Symbols: | Tgfb; Ltbp-1; Ltbp1L; 9830146M04; b2b1000Clo; 9430031G15Rik; TGF-beta1-BP-1 |
| NCBI Protein Information: | latent-transforming growth factor beta-binding protein 1 |
| UniProt Protein Name: | Latent-transforming growth factor beta-binding protein 1 |
| UniProt Synonym Protein Names: | Transforming growth factor beta-1-binding protein 1; TGF-beta1-BP-1 |
| Protein Family: | Latent-transforming growth factor beta-binding protein |
| UniProt Gene Name: | Ltbp1 |
| UniProt Entry Name: |