LTA Monoclonal Antibody [PAT15A3AT] (CPAB0011)
![LTA Monoclonal Antibody [PAT15A3AT] (CPAB0011)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58240/63422/lta-monoclonal-antibody-pat15a3at-cpab0011__58081__80791.1706534942.jpg?c=1 "LTA Monoclonal Antibody [PAT15A3AT] (CPAB0011)")
- SKU:
- CPAB0011
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- PAT15A3AT
- Applications:
- WB
- Applications:
- IF
- Applications:
- ELISA
![LTA Monoclonal Antibody [PAT15A3AT] (CPAB0011)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58240/63422/lta-monoclonal-antibody-pat15a3at-cpab0011__58081__80791.1706534942.jpg?c=1&imbypass=on "LTA Monoclonal Antibody [PAT15A3AT] (CPAB0011)")
Description
system_update_alt Datasheet
| Product Name: | LTA Antibody |
| Product Sku: | CPAB0011 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human LTA mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human LTA amino acids 35-25 purified from Ecoli. |
| Clone: | PAT15A3AT. |
| Reactivity: | Human |
| Applications: | Western Blot, Immunofluorescence, ELISA |
| Purification Method: | LTA antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG2b |
| Background: | Lymphotoxin-alpha (LT-alpha or LTA) belongs to the TNF ligand superfamily, which bind the same TNF receptor and mediate similar pleiotropic effect. LTA is a proinflammatory cytokine with important biological activity and immunomodulatory function and is known to influence a variety of cellular response. Furthermore, LTA mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and has a role in apoptosis. LTA is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. LTA, which is located within the MHC III region of chromosome 6, shows close relation to the HLA class I (HLA-B) and class II (HLA-DR) genes. Polymorphism in the LTA gene appears to contribute to infectious disease susceptibility and infection. Genetic variations in the LTA gene are linked to susceptibility to leprosy type 4 and psoriatic arthritis. |
| Synonyms: | Lymphotoxin-alpha, LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA, TNFB, TNFSF1, LT. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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