Description
Antibody Name: | LSM7 Antibody (PACO42326) |
Antibody SKU: | PACO42326 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human U6 snRNA-associated Sm-like protein LSm7 protein (2-103AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: LSM7 antibody at 3µg/ml + HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 12 kDa. Observed band size: 12 kDa. |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO42326 at dilution of 1:100. |
Background: | Binds specifically to the 3'-terminal U-tract of U6 snRNA and is probably a component of the spliceosome. |
Synonyms: | U6 snRNA-associated Sm-like protein LSm7, LSM7 |
UniProt Protein Function: | LSM7: Binds specifically to the 3'-terminal U-tract of U6 snRNA. Belongs to the snRNP Sm proteins family. |
UniProt Protein Details: | Protein type:Spliceosome; RNA splicing Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: spliceosome; cytosol Molecular Function:protein binding; U6 snRNA binding Biological Process: RNA splicing; gene expression; mRNA processing; mRNA catabolic process, deadenylation-dependent decay |
NCBI Summary: | Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004] |
UniProt Code: | Q9UK45 |
NCBI GenInfo Identifier: | 10720075 |
NCBI Gene ID: | 51690 |
NCBI Accession: | Q9UK45.1 |
UniProt Related Accession: | Q9UK45 |
Molecular Weight: | 103 |
NCBI Full Name: | U6 snRNA-associated Sm-like protein LSm7 |
NCBI Synonym Full Names: | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
NCBI Official Symbol: | LSM7 |
NCBI Official Synonym Symbols: | YNL147W |
NCBI Protein Information: | U6 snRNA-associated Sm-like protein LSm7 |
UniProt Protein Name: | U6 snRNA-associated Sm-like protein LSm7 |
Protein Family: | Sm-like protein |
UniProt Gene Name: | LSM7 |
UniProt Entry Name: | LSM7_HUMAN |
Antibodies |
LSM7 Antibody (PACO10304) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |