Description
| Antibody Name: | LSM5 Antibody (PACO10303) |
| Antibody SKU: | PACO10303 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human LSM5 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae);LSM5;FLJ12710;YER146W ; |
| UniProt Protein Function: | LSM5: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro. Belongs to the snRNP Sm proteins family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: RNA-binding; RNA processingChromosomal Location of Human Ortholog: 7p14.3Cellular Component: cytosol; nucleoplasm; nucleus; spliceosome; U4/U6 x U5 tri-snRNP complexMolecular Function: protein binding; RNA bindingBiological Process: mRNA processing; nuclear mRNA splicing, via spliceosome |
| UniProt Protein Details: | |
| NCBI Summary: | Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004] |
| UniProt Code: | Q9Y4Y9 |
| NCBI GenInfo Identifier: | 6912488 |
| NCBI Gene ID: | 23658 |
| NCBI Accession: | NP_036454.1 |
| UniProt Secondary Accession: | Q9Y4Y9 |
| UniProt Related Accession: | Q9Y4Y9 |
| Molecular Weight: | 6,850 Da |
| NCBI Full Name: | U6 snRNA-associated Sm-like protein LSm5 isoform a |
| NCBI Synonym Full Names: | LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated |
| NCBI Official Symbol: | LSM5 |
| NCBI Official Synonym Symbols: | YER146W |
| NCBI Protein Information: | U6 snRNA-associated Sm-like protein LSm5 |
| UniProt Protein Name: | U6 snRNA-associated Sm-like protein LSm5 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Sm-like protein |
| UniProt Gene Name: | LSM5 |
| UniProt Entry Name: | LSM5_HUMAN |