LRRN2 Antibody (PACO28025)
- SKU:
- PACO28025
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | LRRN2 Antibody (PACO28025) |
| Antibody SKU: | PACO28025 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Leucine-rich repeat neuronal protein 2 protein (201-500AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO28025 at dilution of 1:100. |
 | Immunofluorescent analysis of A549 cells using PACO28025 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | receptor activity, cell adhesion, signal transduction |
| Synonyms: | Leucine-rich repeat neuronal protein 2 (Glioma amplified on chromosome 1 protein) (Leucine-rich repeat neuronal protein 5), LRRN2, GAC1 LRRN5 |
| UniProt Protein Function: | LRRN2: Protein type: Membrane protein, integral; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 1q32.1Cellular Component: integral to membraneMolecular Function: receptor activityBiological Process: signal transduction; cell adhesion |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O75325 |
| NCBI GenInfo Identifier: | 42544231 |
| NCBI Gene ID: | 10446 |
| NCBI Accession: | NP_006329.2 |
| UniProt Secondary Accession: | O75325,Q5T0Y0, Q6UXM0, Q8N182, B2R624 |
| UniProt Related Accession: | O75325 |
| Molecular Weight: | 78,859 Da |
| NCBI Full Name: | leucine-rich repeat neuronal protein 2 |
| NCBI Synonym Full Names: | leucine rich repeat neuronal 2 |
| NCBI Official Symbol: | LRRN2 |
| NCBI Official Synonym Symbols: | GAC1; LRRN5; LRANK1; FIGLER7 |
| NCBI Protein Information: | leucine-rich repeat neuronal protein 2; leucine rich repeat neuronal 5; leucine rich and ankyrin repeats 1; leucine-rich repeat neuronal protein 5; glioma amplified on chromosome 1 protein; fibronectin type III, immunoglobulin and leucine rich repeat domain 7 |
| UniProt Protein Name: | Leucine-rich repeat neuronal protein 2 |
| UniProt Synonym Protein Names: | Glioma amplified on chromosome 1 protein; Leucine-rich repeat neuronal protein 5 |
| Protein Family: | Leucine-rich repeat neuronal protein |
| UniProt Gene Name: | LRRN2 |
| UniProt Entry Name: | LRRN2_HUMAN |
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