LRRC15 Antibody (PACO38042)
- SKU:
- PACO38042
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | LRRC15 Antibody (PACO38042) |
| Antibody SKU: | PACO38042 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Leucine-rich repeat-containing protein 15 protein (301-538AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human heart tissue using PACO38042 at dilution of 1:100. |
 | Immunofluorescence staining of SH-SY5Y cells with PACO38042 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | extracellular exosome, collagen binding, fibronectin binding, laminin binding, negative regulation of establishment of protein localization to plasma membrane, positive regulation of cell migration, receptor-mediated virion attachment to host cell |
| Synonyms: | Leucine-rich repeat-containing protein 15 (Leucine-rich repeat protein induced by beta-amyloid homolog) (hLib), LRRC15, LIB |
| UniProt Protein Function: | LRRC15: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 3q29Cellular Component: integral to membraneMolecular Function: collagen binding; fibronectin binding; laminin bindingBiological Process: virion attachment, binding of host cell surface receptor; positive regulation of cell migration |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8TF66 |
| NCBI GenInfo Identifier: | 288541295 |
| NCBI Gene ID: | 131578 |
| NCBI Accession: | NP_001128529.2 |
| UniProt Secondary Accession: | Q8TF66,Q495Q6, Q7RTN7 |
| UniProt Related Accession: | Q8TF66 |
| Molecular Weight: | 64,366 Da |
| NCBI Full Name: | leucine-rich repeat-containing protein 15 isoform a |
| NCBI Synonym Full Names: | leucine rich repeat containing 15 |
| NCBI Official Symbol: | LRRC15 |
| NCBI Official Synonym Symbols: | LIB |
| NCBI Protein Information: | leucine-rich repeat-containing protein 15; hLib; leucine-rich repeat protein induced by beta amyloid; leucine-rich repeat protein induced by beta-amyloid homolog |
| UniProt Protein Name: | Leucine-rich repeat-containing protein 15 |
| UniProt Synonym Protein Names: | Leucine-rich repeat protein induced by beta-amyloid homolog; hLib |
| Protein Family: | Leucine-rich repeat-containing protein |
| UniProt Gene Name: | LRRC15 |
| UniProt Entry Name: | LRC15_HUMAN |
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