LRP/MVP Monoclonal Antibody
- SKU:
- CAB24944
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | LRP/MVP Monoclonal Antibody |
| Product Code: | CAB24944 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC64517 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:2000-1:8000, IHC-P 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | C6 |
| Cellular Location: | Cytoplasm, Nucleus, nuclear pore complex |
This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-370 of Human LRP/MVP(NP_034146.2). |
| Sequence: | MATEE FIIRI PPYHY IHVLD QNSNV SRVEV GPKTY IRQDN ERVLF APMRM VTVPP RHYCT VANPV SRDAQ GLVLF DVTGQ VRLRH ADLEI RLAQD PFPLY PGEVL EKDIT PLQVV LPNTA LHLKA LLDFE DKDGD KVVAG DEWLF EGPGT YIPRK EVEVV EIIQA TIIRQ NQALR LRARK ECWDR DGKER VTGEE WLVTT VGAYL PAVFE EVLDL VDAVI LTEKT ALHLR ARRNF RDFRG VSRRT GEEWL VTVQD TEAHV PDVHE EVLGV VPITT LGPHN YCVIL DPVGP DGKNQ LGQKR VVKGE KSFFL QPGEQ LEQGI QDVYV LSEQQ GLLLR ALQPL EEGED EEKVS HQAGD HWLIR GPLEY VPSAK |
| Synonyms: | LRP, VAULT1 |
| Calculated MW: | 99kDa |
| Observed MW: | 110kDa |
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