LRIG3 Antibody (PACO18165)
- SKU:
- PACO18165
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | LRIG3 Antibody (PACO18165) |
| Antibody SKU: | PACO18165 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human LRIG3 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO18165(LRIG3 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Leucine-rich repeats and immunoglobulin-like domains 3 (Lrig3) was identified by microarray analysis among genes that show differential expression during gastrulation in Xenopus laevis. Lrig3 was expressed in the neural plate and neural crest (NC) at neurula stages, and in NC derivatives and other dorsal structures during tailbud stages. A prominent consequence of the morpholino-induced inhibition of Lrig3 expression was impaired NC formation, as revealed by the suppression of marker genes, including Slug, Sox9 and Foxd3. |
| Synonyms: | leucine-rich repeats and immunoglobulin-like domains 3 |
| UniProt Protein Function: | LRIG3: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 12q14.1Cellular Component: extracellular space |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6UXM1 |
| NCBI GenInfo Identifier: | 73621176 |
| NCBI Gene ID: | 121227 |
| NCBI Accession: | Q6UXM1.1 |
| UniProt Secondary Accession: | Q6UXM1,Q6UXL7, Q8NC72 |
| UniProt Related Accession: | Q6UXM1 |
| Molecular Weight: | 117,438 Da |
| NCBI Full Name: | Leucine-rich repeats and immunoglobulin-like domains protein 3 |
| NCBI Synonym Full Names: | leucine rich repeats and immunoglobulin like domains 3 |
| NCBI Official Symbol: | LRIG3 |
| NCBI Official Synonym Symbols: | LIG3 |
| NCBI Protein Information: | leucine-rich repeats and immunoglobulin-like domains protein 3 |
| UniProt Protein Name: | Leucine-rich repeats and immunoglobulin-like domains protein 3 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Leucine-rich repeats and immunoglobulin-like domains protein |
| UniProt Gene Name: | LRIG3 |
| UniProt Entry Name: | LRIG3_HUMAN |
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