lpxC Antibody (PACO34762)
- SKU:
- PACO34762
- Product Type:
- Antibody
- Reactivity:
- Bacteria - Escherichia coli
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | lpxC Antibody (PACO34762) |
| Antibody SKU: | PACO34762 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Escherichia coli |
| Immunogen: | Recombinant Escherichia coli UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase protein (1-305AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | The key enzyme in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Degraded by FtsH; when the activity of FtsH is reduced too much lipid A and not enough phospholipids are made (both pathways use the same precursor), which is lethal. |
| Synonyms: | UDP-3-O-acyl-N-acetylglucosamine deacetylase (UDP-3-O-acyl-GlcNAc deacetylase) (EC 3.5.1.108) (Protein EnvA) (UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase), lpxC, asmB envA |
| UniProt Protein Function: | Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. |
| UniProt Protein Details: | |
| NCBI Summary: | LpxC regulated degradation is facilitated by FtsH. [More information is available at EcoGene: EG10265]. UDP-3-O-acyl-N-acetylglucosamine deacetylase (LpxC) catalyzes the second reaction and the first committed step in lipid A biosynthesis. [More information is available at EcoCyc: EG10265]. |
| UniProt Code: | P0A725 |
| NCBI GenInfo Identifier: | 16128089 |
| NCBI Gene ID: | 944816 |
| NCBI Accession: | NP_414638.1 |
| UniProt Secondary Accession: | P0A725,P07652 |
| UniProt Related Accession: | P0A725 |
| Molecular Weight: | |
| NCBI Full Name: | UDP-3-O-acyl N-acetylglucosamine deacetylase |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | lpxC |
| NCBI Official Synonym Symbols: | asmB; ECK0097; envA; JW0094 |
| NCBI Protein Information: | UDP-3-O-acyl N-acetylglucosamine deacetylase |
| UniProt Protein Name: | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase |
| UniProt Synonym Protein Names: | Protein EnvA; UDP-3-O-acyl-GlcNAc deacetylase |
| Protein Family: | UDP-3-O-acyl-N-acetylglucosamine deacetylase |
| UniProt Gene Name: | lpxC |
| UniProt Entry Name: | LPXC_ECOLI |
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