LPGAT1 Antibody (PACO38090)
- SKU:
- PACO38090
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | LPGAT1 Antibody (PACO38090) |
| Antibody SKU: | PACO38090 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:200-1:3000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 protein (151-341AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human liver cancer using PACO38090 at dilution of 1:100. |
 | Western Blot. Positive WB detected in: HEK293 whole cell lysate, Hela whole cell lysate. All lanes: LPGAT1 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 44 kDa. Observed band size: 44 kDa. |
| Background: | Lysophosphatidylglycerol (LPG) specific acyltransferase that recognizes various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl-CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor. |
| Synonyms: | Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (EC 2.3.1.-), LPGAT1, FAM34A KIAA0205 |
| UniProt Protein Function: | LPGAT1: Lysophoshatidylglycerol (LPG) specific acyltransferase that recognizes various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl-CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.Protein type: EC 2.3.1.-; Membrane protein, multi-pass; Transferase; Membrane protein, integralChromosomal Location of Human Ortholog: 1q32Cellular Component: cytoplasm; endoplasmic reticulum membrane; membraneMolecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity; 2-acylglycerol-3-phosphate O-acyltransferase activity |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the lysophospholipid acyltransferase family. The encoded protein catalyzes the reacylation of lysophosphatidylglycerol to phosphatidylglycerol, a membrane phospholipid that is an important precursor for the synthesis of cardiolipin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
| UniProt Code: | Q92604 |
| NCBI GenInfo Identifier: | 6136501 |
| NCBI Gene ID: | 9926 |
| NCBI Accession: | Q92604.1 |
| UniProt Secondary Accession: | Q92604,Q53YL2 |
| UniProt Related Accession: | Q92604 |
| Molecular Weight: | 43,089 Da |
| NCBI Full Name: | Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 |
| NCBI Synonym Full Names: | lysophosphatidylglycerol acyltransferase 1 |
| NCBI Official Symbol: | LPGAT1 |
| NCBI Official Synonym Symbols: | NET8; FAM34A; FAM34A1 |
| NCBI Protein Information: | acyl-CoA:lysophosphatidylglycerol acyltransferase 1 |
| UniProt Protein Name: | Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Acyl-CoA:lysophosphatidylglycerol acyltransferase |
| UniProt Gene Name: | LPGAT1 |
| UniProt Entry Name: | LGAT1_HUMAN |
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