LPAR5 Antibody (PACO61947)
- SKU:
- PACO61947
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | LPAR5 Antibody (PACO61947) |
| Antibody SKU: | PACO61947 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Peptide sequence from Human Lysophosphatidic acid, receptor 5 protein (310-326AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO61947 diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | Immunofluorescence staining of Hela cells with PACO61947 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Receptor for lysophosphatidic acid, (LPA), a mediator of diverse cellular activities. |
| Synonyms: | Lysophosphatidic acid, receptor 5 (LPA receptor 5) (LPA-5) (G-protein coupled receptor 92) (G-protein coupled receptor 93), LPAR5, GPR92 GPR93 |
| UniProt Protein Function: | GPR92: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1Chromosomal Location of Human Ortholog: 12p13.31Cellular Component: integral to membrane; plasma membraneMolecular Function: G-protein coupled receptor activityBiological Process: G-protein coupled receptor protein signaling pathway |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the rhodopsin class of G protein-coupled transmembrane receptors. This protein transmits extracellular signals from lysophosphatidic acid to cells through heterotrimeric G proteins and mediates numerous cellular processes. Many G protein receptors serve as targets for pharmaceutical drugs. Transcript variants of this gene have been described.[provided by RefSeq, Dec 2008] |
| UniProt Code: | Q9H1C0 |
| NCBI GenInfo Identifier: | 219281887 |
| NCBI Gene ID: | 57121 |
| NCBI Accession: | NP_001136433.1 |
| UniProt Secondary Accession: | Q9H1C0 |
| UniProt Related Accession: | Q9H1C0 |
| Molecular Weight: | 41,347 Da |
| NCBI Full Name: | lysophosphatidic acid receptor 5 |
| NCBI Synonym Full Names: | lysophosphatidic acid receptor 5 |
| NCBI Official Symbol: | LPAR5 |
| NCBI Official Synonym Symbols: | LPA5; GPR92; GPR93; KPG_010 |
| NCBI Protein Information: | lysophosphatidic acid receptor 5 |
| UniProt Protein Name: | Lysophosphatidic acid receptor 5 |
| UniProt Synonym Protein Names: | G-protein coupled receptor 92; G-protein coupled receptor 93 |
| Protein Family: | Lysophosphatidic acid receptor |
| UniProt Gene Name: | LPAR5 |
| UniProt Entry Name: | LPAR5_HUMAN |
| Antibodies |
| LPAR5 Antibody (PACO00881) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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