LOXHD1 Antibody (PACO50778)
- SKU:
- PACO50778
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | LOXHD1 Antibody (PACO50778) |
| Antibody SKU: | PACO50778 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Lipoxygenase homology domain-containing protein 1 protein (1101-1366AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO50778 at dilution of 1:100. |
 | Immunofluorescent analysis of HepG2 cells using PACO50778 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Involved in hearing. Required for normal function of hair cells in the inner ear (By similarity). |
| Synonyms: | Lipoxygenase homology domain-containing protein 1, LOXHD1 |
| UniProt Protein Function: | Involved in hearing. Required for normal function of hair cells in the inner ear (). |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a highly conserved protein consisting entirely of PLAT (polycystin/lipoxygenase/alpha-toxin) domains, thought to be involved in targeting proteins to the plasma membrane. Studies in mice show that this gene is expressed in the mechanosensory hair cells in the inner ear, and mutations in this gene lead to auditory defects, indicating that this gene is essential for normal hair cell function. Screening of human families segregating deafness identified a mutation in this gene which causes DFNB77, a progressive form of autosomal-recessive nonsyndromic hearing loss (ARNSHL). Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2010] |
| UniProt Code: | Q8IVV2 |
| NCBI GenInfo Identifier: | 808688336 |
| NCBI Gene ID: | 125336 |
| NCBI Accession: | NP_001294942.1 |
| UniProt Secondary Accession: | Q8IVV2,Q6ZRY7, Q86WW9, Q96DL7, B7WNN3, B7WNT1, B7WPI9 |
| UniProt Related Accession: | Q8IVV2 |
| Molecular Weight: | |
| NCBI Full Name: | lipoxygenase homology domain-containing protein 1 isoform 5 |
| NCBI Synonym Full Names: | lipoxygenase homology domains 1 |
| NCBI Official Symbol: | LOXHD1 |
| NCBI Official Synonym Symbols: | LH2D1; DFNB77 |
| NCBI Protein Information: | lipoxygenase homology domain-containing protein 1 |
| UniProt Protein Name: | Lipoxygenase homology domain-containing protein 1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Lipoxygenase homology domain-containing protein |
| UniProt Gene Name: | LOXHD1 |
| UniProt Entry Name: |
Related Products
SPEF2 Antibody
Overview Product Name:SPEF2 AntibodyProduct Code:PACO64977Size:50µLTarget Names:SPEF2Species Reactivity:HumanHos
ompF Antibody
Overview Product Name:ompF AntibodyProduct Code:PACO64865Size:50µLTarget Names:ompFSpecies Reactivity:Escherichia coli
Hmgb1 Antibody
Overview Product Name:Hmgb1 AntibodyProduct Code:PACO64769Size:50µLTarget Names:Hmgb1Species Reactivity:RatHost
RIMS4 Antibody
Overview Product Name:RIMS4 AntibodyProduct Code:PACO64925Size:50µLTarget Names:RIMS4Species Reactivity:HumanHos
C22orf39 Antibody
Overview Product Name:C22orf39 AntibodyProduct Code:PACO64621Size:50µLTarget Names:C22orf39Species Reactivity:Human<