lktA Antibody (PACO34106)
- SKU:
- PACO34106
- Product Type:
- Antibody
- Reactivity:
- Bacteria
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | lktA Antibody (PACO34106) |
| Antibody SKU: | PACO34106 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mannheimia haemolytica |
| Immunogen: | Recombinant Mannheimia haemolytica Leukotoxin protein (715-953AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | Leukotoxin (Lkt), lktA |
| UniProt Protein Function: | Pasteurella leukotoxins are exotoxins that attack host leukocytes and especially polymorphonuclear cells, by causing cell rupture. The leukotoxin binds to the host LFA-1 integrin and induces a signaling cascade leading to many biological effects, including tyrosine phosphorylation of the CD18 tail, elevation of the intracellular Ca2+ and lysis of the host cell (). This leukotoxin is a major contributor to the pathogenesis of lung injury in ovine pneumonic pasteurellosis. It has also weak hemolytic activity. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P0C085 |
| NCBI GenInfo Identifier: | 73621161 |
| NCBI Gene ID: | |
| NCBI Accession: | P0C085.1 |
| UniProt Secondary Accession: | P0C085,Q9EV28 |
| UniProt Related Accession: | P0C085 |
| Molecular Weight: | 28 kDa |
| NCBI Full Name: | Leukotoxin |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Leukotoxin |
| UniProt Synonym Protein Names: | |
| Protein Family: | Leukotoxin |
| UniProt Gene Name: | lktA |
| UniProt Entry Name: | LKA7B_MANHA |
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