Description
| Product Name: | LKB1 Monoclonal Antibody |
| Product Code: | CAB22636 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC58343 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IP, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
| Recommended Dilution: | WB 1:2000-1:8000, IHC-P 1:50-1:200, IP 1:2000-1:8000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, MCF7, L929, mouse testis, PC-12 |
| Cellular Location: | Cytoplasm, Membrane, Mitochondrion, Nucleus |
The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with the autosomal dominant Peutz-Jeghers syndrome, as well as with skin, pancreatic, and testicular cancers.
| Immunogen: | Recombinant protein of human LKB1. |
| Sequence: | Email for sequence |
| Synonyms: | PJS, LKB1, hLKB1 |
| Calculated MW: | 49kDa |
| Observed MW: | 49-60kDa |