Description
Antibody Name: | LIN37 Antibody (PACO38466) |
Antibody SKU: | PACO38466 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Protein lin-37 homolog protein (1-246AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO38466 at dilution of 1:100. |
Background: | nucleoplasm, G2/M transition of mitotic cell cycle, mitotic cell cycle, regulation of cell cycle |
Synonyms: | Protein lin-37 homolog (Antolefinin), LIN37 |
UniProt Protein Function: | F25965: Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2.Chromosomal Location of Human Ortholog: 19q13.1Cellular Component: nucleoplasm; transcriptional repressor complexMolecular Function: protein bindingBiological Process: G2/M transition of mitotic cell cycle; mitotic cell cycle; regulation of cell cycle |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a protein expressed in the eye. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q96GY3 |
NCBI GenInfo Identifier: | 28144916 |
NCBI Gene ID: | 55957 |
NCBI Accession: | NP_061977.1 |
UniProt Secondary Accession: | Q96GY3,O14557, Q7Z2T9, A8KAQ1 |
UniProt Related Accession: | Q96GY3 |
Molecular Weight: | 28,383 Da |
NCBI Full Name: | protein lin-37 homolog |
NCBI Synonym Full Names: | lin-37 DREAM MuvB core complex component |
NCBI Official Symbol: | LIN37 |
NCBI Official Synonym Symbols: | F25965; lin-37; ZK418.4 |
NCBI Protein Information: | protein lin-37 homolog |
UniProt Protein Name: | Protein lin-37 homolog |
UniProt Synonym Protein Names: | Antolefinin |
Protein Family: | Protein |
UniProt Gene Name: | LIN37 |
UniProt Entry Name: | LIN37_HUMAN |