Lilrb3 Antibody (PACO27965)
- SKU:
- PACO27965
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Lilrb3 Antibody (PACO27965) |
| Antibody SKU: | PACO27965 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Leukocyte immunoglobulin-like receptor subfamily B member 3 protein (664-841AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM). |
| Synonyms: | Leukocyte immunoglobulin-like receptor subfamily B member 3 (LIR-3) (Leukocyte immunoglobulin-like receptor 3) (Cell-surface glycoprotein p91) (Paired immunoglobulin-like receptor B) (PIR-B), Lilrb3, Pirb |
| UniProt Protein Function: | Pirb: May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B- cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).Protein type: Membrane protein, integralCellular Component: integral to membrane; membrane; plasma membraneBiological Process: adaptive immune response; B cell homeostasis; B cell mediated immunity; cytokine and chemokine mediated signaling pathway; immune system process; myeloid dendritic cell differentiation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P97484 |
| NCBI GenInfo Identifier: | 160333134 |
| NCBI Gene ID: | 18733 |
| NCBI Accession: | NP_035225.2 |
| UniProt Secondary Accession: | P97484 |
| UniProt Related Accession: | P97484 |
| Molecular Weight: | 93,054 Da |
| NCBI Full Name: | leukocyte immunoglobulin-like receptor subfamily B member 3 |
| NCBI Synonym Full Names: | paired Ig-like receptor B |
| NCBI Official Symbol: | Pirb |
| NCBI Official Synonym Symbols: | Gp91; LIR-3; PIR-B; Lilrb3 |
| NCBI Protein Information: | leukocyte immunoglobulin-like receptor subfamily B member 3 |
| UniProt Protein Name: | Leukocyte immunoglobulin-like receptor subfamily B member 3 |
| UniProt Synonym Protein Names: | Cell-surface glycoprotein p91; Paired immunoglobulin-like receptor B; PIR-B |
| Protein Family: | |
| UniProt Gene Name: | Lilrb3 |
| UniProt Entry Name: | LIRB3_MOUSE |
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