LEP Antibody (PACO16613)
- SKU:
- PACO16613
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | LEP Antibody (PACO16613) |
| Antibody SKU: | PACO16613 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:30-1:150 |
| Species Reactivity: | Human |
| Immunogen: | Full length fusion protein |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16613(LEP Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. |
| Synonyms: | leptin |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6NT58 |
| NCBI GenInfo Identifier: | 74758115 |
| NCBI Gene ID: | 0 |
| NCBI Accession: | Q6NT58 |
| UniProt Secondary Accession: | Q6NT58 |
| UniProt Related Accession: | Q6NT58 |
| Molecular Weight: | 16.2 |
| NCBI Full Name: | Leptin |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Leptin |
| UniProt Synonym Protein Names: | Obesity factor |
| Protein Family: | Leptin |
| UniProt Gene Name: | LEP |
| UniProt Entry Name: |
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