LEF1 Monoclonal Antibody
- SKU:
- CAB23458
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IP
Description
| Product Name: | LEF1 Monoclonal Antibody |
| Product Code: | CAB23458 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC57430 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, IHC-P, IP, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
| Recommended Dilution: | WB 1:2000-1:10000, IHC-P 1:500-1:1000, IP 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Jurkat, U-937(Negative control), Mouse thymus |
| Cellular Location: | Nucleus |
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
| Immunogen: | Recombinant protein of human LEF1. |
| Sequence: | Email for sequence |
| Synonyms: | LEF-1, TCF10, TCF7L3, TCF1ALPHA |
| Calculated MW: | 44kDa |
| Observed MW: | 25-60kDa |
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