Description
Product Name: | LDHA Polyclonal Antibody |
Product Code: | CAB21741 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | HeLa |
Cellular Location: | Cytoplasm |
The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-332 of human LDHA (NP_005557.1). |
Sequence: | MATLK DQLIY NLLKE EQTPQ NKITV VGVGA VGMAC AISIL MKDLA DELAL VDVIE DKLKG EMMDL QHGSL FLRTP KIVSG KDYNV TANSK LVIIT AGARQ QEGES RLNLV QRNVN IFKFI IPNVV KYSPN CKLLI VSNPV DILTY VAWKI SGFPK NRVIG SGCNL DSARF RYLMG ERLGV HPLSC HGWVL GEHGD SSVPV WSGMN VAGVS LKTLH PDLGT DKDKE QWKEV HKQVV ESAYE VIKLK GYTSW AIGLS VADLA ESIMK NLRRV HPVST MIKGL YGIKD DVFLS VPCIL GQNGI SDLVK VTLTS EEEAR LKKSA DTLWG IQKEL QF |
Synonyms: | LDHM, GSD11, PIG19, HEL-S-133P |
Calculated MW: | 37kDa |
Observed MW: | 37kDa |