ldcA Antibody (PACO34016)
- SKU:
- PACO34016
- Product Type:
- Antibody
- Reactivity:
- Bacteria - Escherichia coli
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ldcA Antibody (PACO34016) |
| Antibody SKU: | PACO34016 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Escherichia coli |
| Immunogen: | Recombinant Escherichia coli Murein tetrapeptide carboxypeptidase protein (1-304AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.1mol/L NaCl, 15mmol/L NaN3, PH7.2 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso-Dap-D-Ala. To a lesser extent, can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc-tetrapeptide, GlcNAc-MurNAc-tetrapeptide, and GlcNAc-anhMurNAc-tetrapeptide. Does not act on murein sacculi or cross-linked muropeptides. The tripeptides produced by the LcdA reaction can then be reused as peptidoglycan building blocks; LcdA is thereby involved in murein recycling. Is also essential for viability during stationary phase. |
| Synonyms: | Murein tetrapeptide carboxypeptidase (EC 3.4.17.13) (LD-carboxypeptidase A) (Muramoyltetrapeptide carboxypeptidase), ldcA, ycgQ |
| UniProt Protein Function: | Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso-Dap-D-Ala. To a lesser extent, can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc-tetrapeptide, GlcNAc-MurNAc-tetrapeptide, and GlcNAc-anhMurNAc-tetrapeptide. Does not act on murein sacculi or cross-linked muropeptides. The tripeptides produced by the LcdA reaction can then be reused as peptidoglycan building blocks; LcdA is thereby involved in murein recycling. Is also essential for viability during stationary phase. |
| UniProt Protein Details: | |
| NCBI Summary: | LdcA mutants can lyse in stationary phase (Templin, 1999; Herve, 2007). [More information is available at EcoGene: EG13898]. LdcA is an L,D-carboxypeptidase that has an essential function in murein (peptidoglycan) recycling/turnover . [More information is available at EcoCyc: G6621]. |
| UniProt Code: | P76008 |
| NCBI GenInfo Identifier: | 16129155 |
| NCBI Gene ID: | 945756 |
| NCBI Accession: | NP_415710.1 |
| UniProt Secondary Accession: | P76008,O87499 |
| UniProt Related Accession: | P76008 |
| Molecular Weight: | |
| NCBI Full Name: | murein tetrapeptide carboxypeptidase; LD-carboxypeptidase A |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | ldcA |
| NCBI Official Synonym Symbols: | ECK1180; JW1181; ycgQ |
| NCBI Protein Information: | murein tetrapeptide carboxypeptidase; LD-carboxypeptidase A |
| UniProt Protein Name: | Murein tetrapeptide carboxypeptidase |
| UniProt Synonym Protein Names: | LD-carboxypeptidase A; Muramoyltetrapeptide carboxypeptidase |
| Protein Family: | Murein tetrapeptide carboxypeptidase |
| UniProt Gene Name: | ldcA |
| UniProt Entry Name: | LDCA_ECOLI |
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