Description
| Product Name: | LC3B Polyclonal Antibody |
| Product Code: | CAB19434 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:2000, IF/ICC 1:50-1:200, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Positive Samples: | Rat brain |
| Cellular Location: | Cytoplasm, Cytoplasmic vesicle, Endomembrane system, Lipid-anchor, autophagosome, autophagosome membrane, cytoskeleton |
The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LC3B (NP_073729.1). |
| Sequence: | MPSEK TFKQR RTFEQ RVEDV RLIRE QHPTK IPVII ERYKG EKQLP VLDKT KFLVP DHVNM SELIK IIRRR LQLNA NQAFF LLVNG HSMVS VSTPI SEVYE |
| Synonyms: | LC3B, ATG8F, MAP1LC3B-a, MAP1A/1BLC3 |
| Calculated MW: | 15kDa |
| Observed MW: | 15kDa |
