LC3B Polyclonal Antibody (CAB19434)

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SKU:
CAB19434
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
Applications:
IF
Applications:
IHC

Description

Product Name:LC3B Polyclonal Antibody
Product Code:CAB19434
Reactivity:Human, Mouse, Rat
Applications:Western blotting, Immunofluorescence, Immunohistochemistry
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Mouse, Rat
Tested Applications:WB, IHC-P, IF/ICC, ELISA
Key Applications:Western blotting, Immunofluorescence, Immunohistochemistry
Recommended Dilution:WB 1:500-1:2000, IF/ICC 1:50-1:200, IHC-P 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Positive Samples:Rat brain
Cellular Location:Cytoplasm, Cytoplasmic vesicle, Endomembrane system, Lipid-anchor, autophagosome, autophagosome membrane, cytoskeleton

The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LC3B (NP_073729.1).
Sequence:MPSEK TFKQR RTFEQ RVEDV RLIRE QHPTK IPVII ERYKG EKQLP VLDKT KFLVP DHVNM SELIK IIRRR LQLNA NQAFF LLVNG HSMVS VSTPI SEVYE
Synonyms:LC3B, ATG8F, MAP1LC3B-a, MAP1A/1BLC3
Calculated MW:15kDa
Observed MW:15kDa
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