LC3B Polyclonal Antibody (CAB11923)
- SKU:
- CAB11923
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Applications:
- IP
Description
| Product Name: | LC3B Polyclonal Antibody |
| Product Code: | CAB11923 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, IP, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
| Recommended Dilution: | WB 1:500-1:2000, IHC-P 1:50-1:200, IF/ICC 1:50-1:100, IP 1:20-1:50 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | 293 |
| Cellular Location: | Cytoplasm, Cytoplasmic vesicle, Endomembrane system, Lipid-anchor, autophagosome, autophagosome membrane, cytoskeleton |
| Customer Validation: | IHC(Homo sapiens) |
The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LC3B (NP_073729.1). |
| Sequence: | MPSEK TFKQR RTFEQ RVEDV RLIRE QHPTK IPVII ERYKG EKQLP VLDKT KFLVP DHVNM SELIK IIRRR LQLNA NQAFF LLVNG HSMVS VSTPI SEVYE |
| Synonyms: | LC3B, ATG8F, MAP1LC3B-a, MAP1A/1BLC3 |
| Calculated MW: | 15kDa |
| Observed MW: | 20kDa |
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