Description
| Antibody Name: | LARS2 Antibody (PACO44950) |
| Antibody SKU: | PACO44950 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Probable leucine--tRNA ligase, mitochondrial protein (1-250AA) |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human colon cancer using PACO44950 at dilution of 1:100. |
| Background: | mitochondrial matrix, mitochondrion, leucine-tRNA ligase activity, leucyl-tRNA aminoacylation, tRNA aminoacylation for protein translation |
| Synonyms: | Probable leucine--tRNA ligase, mitochondrial (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS), LARS2, KIAA0028 |
| UniProt Protein Function: | LARS2: a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. [provided by RefSeq, Jul 2008]Protein type: Translation; Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; Mitochondrial; Ligase; EC 6.1.1.4Chromosomal Location of Human Ortholog: 3p21.3Cellular Component: mitochondrion; mitochondrial matrix; cytosolMolecular Function: leucine-tRNA ligase activity; ATP bindingBiological Process: leucyl-tRNA aminoacylation; tRNA aminoacylation for protein translation; regulation of translational fidelity; gene expressionDisease: Perrault Syndrome 4 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q15031 |
| NCBI GenInfo Identifier: | 2501029 |
| NCBI Gene ID: | 23395 |
| NCBI Accession: | Q15031.2 |
| UniProt Secondary Accession: | Q15031 |
| UniProt Related Accession: | Q15031 |
| Molecular Weight: | 903 |
| NCBI Full Name: | Probable leucine--tRNA ligase, mitochondrial |
| NCBI Synonym Full Names: | leucyl-tRNA synthetase 2, mitochondrial |
| NCBI Official Symbol: | LARS2 |
| NCBI Official Synonym Symbols: | LEURS; PRLTS4 |
| NCBI Protein Information: | probable leucine--tRNA ligase, mitochondrial; leucine translase; leucine tRNA ligase 2, mitocondrial; leucine tRNA ligase 2, mitochondrial; probable leucyl-tRNA synthetase, mitochondrial |
| UniProt Protein Name: | Probable leucine--tRNA ligase, mitochondrial |
| UniProt Synonym Protein Names: | Leucyl-tRNA synthetase; LeuRS |
| Protein Family: | Probable leucine--tRNA ligase |
| UniProt Gene Name: | LARS2 |
| UniProt Entry Name: | SYLM_HUMAN |
| Antibodies |
| LARS2 Antibody (PACO10198) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
