LAMTOR3 Polyclonal Antibody
- SKU:
- CAB7573
Description
| Product Name: | LAMTOR3 Polyclonal Antibody |
| Product Code: | CAB7573 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Cytoplasmic side, Late endosome membrane, Peripheral membrane protein |
| Customer Validation: | WB(Mus musculus) ICH(Mus musculus) IF(Mus musculus) ELISA(Mus musculus) |
This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-124 of human LAMTOR3 (NP_068805.1). |
| Sequence: | MADDL KRFLY KKLPS VEGLH AIVVS DRDGV PVIKV ANDNA PEHAL RPGFL STFAL ATDQG SKLGL SKNKS IICYY NTYQV VQFNR LPLVV SFIAS SSANT GLIVS LEKEL APLFE ELRQV VEVS |
| Synonyms: | MP1, MAPBP, MAPKSP1, PRO0633, MAP2K1IP1, Ragulator3 |
| Calculated MW: | 14kDa |
| Observed MW: | Refer to figures |