Description
Product Name: | LAMTOR1 Polyclonal Antibody |
Product Code: | CAB21557 |
Reactivity: | Human |
Applications: | Western blotting, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunofluorescence |
Recommended Dilution: | WB 1:500-1:2000, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
Cellular Location: | Cell membrane, Cytoplasmic side, Late endosome membrane, Lipid-anchor, Lysosome membrane |
Enables GTPase binding activity. Contributes to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Involved in several processes, including cholesterol homeostasis; positive regulation of TOR signaling; and regulation of cholesterol transport. Located in lysosome. Part of Ragulator complex.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-161 of human LAMTOR1 (NP_060377.1). |
Sequence: | MGCCY SSENE DSDQD REERK LLLDP SSPPT KALNG AEPNY HSLPS ARTDE QALLS SILAK TASNI IDVSA ADSQG MEQHE YMDRA RQYST RLAVL SSSLT HWKKL PPLPS LTSQP HQVLA SEPIP FSDLQ QVSRI AAYAY SALSQ IRVDA KEELV VQFGI P |
Synonyms: | p18, PDRO, C11orf59, p27RF-Rho, Ragulator1 |
Calculated MW: | 18kDa |
Observed MW: | Refer to figures |