Description
Antibody Name: | LAMA5 Antibody (PACO27901) |
Antibody SKU: | PACO27901 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Laminin subunit alpha-5 protein (3401-3692AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO27901 at dilution of 1:100. |
Background: | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
Synonyms: | Laminin subunit alpha-5 (Laminin-10 subunit alpha) (Laminin-11 subunit alpha) (Laminin-15 subunit alpha), LAMA5, KIAA0533 KIAA1907 |
UniProt Protein Function: | LAMA5: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted; Extracellular matrix; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 20q13.2-q13.3 Cellular Component: extracellular matrix; extracellular space; laminin-5 complex; laminin-1 complex; laminin-10 complex; extracellular region; basement membrane; basal lamina; nucleus Molecular Function:integrin binding; structural molecule activity Biological Process: integrin-mediated signaling pathway; regulation of cell adhesion; focal adhesion formation; endothelial cell differentiation; extracellular matrix organization and biogenesis; muscle development; cell migration; regulation of embryonic development; cell recognition; cytoskeleton organization and biogenesis; regulation of cell migration; regulation of cell proliferation; odontogenesis of dentine-containing teeth; cell proliferation; extracellular matrix disassembly; embryonic development; morphogenesis of embryonic epithelium; hair follicle development; ureteric bud branching; cilium biogenesis; angiogenesis; cell differentiation; neural crest cell migration; morphogenesis of a polarized epithelium; lung development |
NCBI Summary: | This gene encodes one of the vertebrate laminin alpha chains. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. The protein encoded by this gene is the alpha-5 subunit of of laminin-10 (laminin-511), laminin-11 (laminin-521) and laminin-15 (laminin-523). [provided by RefSeq, Jun 2013] |
UniProt Code: | O15230 |
NCBI GenInfo Identifier: | 21264602 |
NCBI Gene ID: | 3911 |
NCBI Accession: | |
UniProt Related Accession: | O15230 |
Molecular Weight: | |
NCBI Full Name: | laminin subunit alpha-5 |
NCBI Synonym Full Names: | laminin subunit alpha 5 |
NCBI Official Symbol: | LAMA5 |
NCBI Protein Information: | laminin subunit alpha-5 |
UniProt Protein Name: | Laminin subunit alpha-5 |
UniProt Synonym Protein Names: | Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha |
UniProt Gene Name: | LAMA5 |
UniProt Entry Name: | LAMA5_HUMAN |
Antibodies | ELISA Kits |
LAMA5 Antibody (PACO02865) | Human Laminin subunit alpha-5 / LAMA5 ELISA Kit |
Human Laminin subunit alpha-5 (LAMA5) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |