Name: LAMA5 Antibody (PACO02865)
SKU: PACO02865
Availability: OutOfStock

Antibody Name:	LAMA5 Antibody
Antibody SKU:	PACO02865
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:	Human, Mouse
Immunogen:	synthesized peptide derived from the Internal region of human Laminin alpha-5.

Form:	Liquid
Storage Buffer:	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Synonyms:

LAMA5; KIAA0533; KIAA1907; Laminin subunit alpha-5; Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha

UniProt Protein Function:	LAMA5: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
UniProt Protein Details:	Protein type:Secreted, signal peptide; Secreted; Extracellular matrix; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 20q13.2-q13.3 Cellular Component: extracellular matrix; extracellular space; laminin-5 complex; laminin-1 complex; laminin-10 complex; extracellular region; basement membrane; basal lamina; nucleus Molecular Function:integrin binding; structural molecule activity Biological Process: integrin-mediated signaling pathway; regulation of cell adhesion; focal adhesion formation; endothelial cell differentiation; extracellular matrix organization and biogenesis; muscle development; cell migration; regulation of embryonic development; cell recognition; cytoskeleton organization and biogenesis; regulation of cell migration; regulation of cell proliferation; odontogenesis of dentine-containing teeth; cell proliferation; extracellular matrix disassembly; embryonic development; morphogenesis of embryonic epithelium; hair follicle development; ureteric bud branching; cilium biogenesis; angiogenesis; cell differentiation; neural crest cell migration; morphogenesis of a polarized epithelium; lung development
NCBI Summary:	This gene encodes one of the vertebrate laminin alpha chains. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. The protein encoded by this gene is the alpha-5 subunit of of laminin-10 (laminin-511), laminin-11 (laminin-521) and laminin-15 (laminin-523). [provided by RefSeq, Jun 2013]
UniProt Code:	O15230
NCBI GenInfo Identifier:	21264602
NCBI Gene ID:	3911
NCBI Accession:
UniProt Related Accession:	O15230
Molecular Weight:
NCBI Full Name:	laminin subunit alpha-5
NCBI Synonym Full Names:	laminin subunit alpha 5
NCBI Official Symbol:	LAMA5
NCBI Protein Information:	laminin subunit alpha-5
UniProt Protein Name:	Laminin subunit alpha-5
UniProt Synonym Protein Names:	Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha
UniProt Gene Name:	LAMA5
UniProt Entry Name:	LAMA5_HUMAN