LAMA1 Antibody (PACO22064)
- SKU:
- PACO22064
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | LAMA1 Antibody (PACO22064) |
| Antibody SKU: | PACO22064 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:100-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from internal of human LAMA1. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence analysis of COS-7 cells, using LAMA1 antibody. |
| Background: | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
| Synonyms: | LAMA; laminin A; laminin alpha-1; |
| UniProt Protein Function: | LAMA1: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis; Extracellular matrix Chromosomal Location of Human Ortholog: 18p11.3 Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; laminin-1 complex; laminin-3 complex; extracellular region; basement membrane; intercellular junction Molecular Function:protein binding; extracellular matrix structural constituent; glycosphingolipid binding; receptor binding Biological Process: regulation of cell adhesion; axon guidance; extracellular matrix organization and biogenesis; cell surface receptor linked signal transduction; regulation of embryonic development; morphogenesis of an epithelial sheet; establishment of epithelial cell polarity; cell adhesion; regulation of cell migration Disease: Poretti-boltshauser Syndrome |
| NCBI Summary: | This gene encodes one of the alpha 1 subunits of laminin. The laminins are a family of extracellular matrix glycoproteins that have a heterotrimeric structure consisting of an alpha, beta and gamma chain. These proteins make up a major component of the basement membrane and have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Mutations in this gene may be associated with Poretti-Boltshauser syndrome. [provided by RefSeq, Sep 2014] |
| UniProt Code: | P25391 |
| NCBI GenInfo Identifier: | 38788416 |
| NCBI Gene ID: | 284217 |
| NCBI Accession: | NP_005550.2 |
| UniProt Related Accession: | P25391 |
| Molecular Weight: | 337,084 Da |
| NCBI Full Name: | laminin subunit alpha-1 |
| NCBI Synonym Full Names: | laminin, alpha 1 |
| NCBI Official Symbol: | LAMA1 |
| NCBI Official Synonym Symbols: | LAMA; PTBHS; S-LAM-alpha |
| NCBI Protein Information: | laminin subunit alpha-1; S-LAM alpha; S-laminin subunit alpha; laminin A chain; laminin-3 subunit alpha |
| UniProt Protein Name: | Laminin subunit alpha-1 |
| UniProt Synonym Protein Names: | Laminin A chain; Laminin-1 subunit alpha; Laminin-3 subunit alpha; S-laminin subunit alpha; S-LAM alpha |
| Protein Family: | Laminin |
| UniProt Gene Name: | LAMA1 |
| UniProt Entry Name: | LAMA1_HUMAN |
| Antibodies | ELISA Kits |
| LAMA1 Antibody (PACO03931) | Human Laminin subunit alpha-1 / LAMA1 ELISA Kit |
| Human Laminin subunit alpha-1 (LAMA1) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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