L3HYPDH Antibody (PACO39306)
- SKU:
- PACO39306
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | L3HYPDH Antibody (PACO39306) |
| Antibody SKU: | PACO39306 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Trans-3-hydroxy-L-proline dehydratase protein (13-312AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: L3HYPDH antibody at 8µg/ml. Lane 1: HepG2 whole cell lysate. Lane 2: A549 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 39 kDa. Observed band size: 39 kDa. |
 | Immunohistochemistry of paraffin-embedded human lung cancer using PACO39306 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO39306 at dilution of 1:100. |
| Background: | Catalyzes the dehydration of trans-3-hydroxy-L-proline to Delta(1)-pyrroline-2-carboxylate (Pyr2C). May be required to degrade trans-3-hydroxy-L-proline from the diet and originating from the degradation of proteins such as collagen-IV that contain it. |
| Synonyms: | Trans-3-hydroxy-L-proline dehydratase (EC 4.2.1.77) (Trans-L-3-hydroxyproline dehydratase), L3HYPDH, C14orf149 |
| UniProt Protein Function: | L3HYPDH: Catalyzes the dehydration of trans-3-hydroxy-L-proline to delta-1-pyrroline-2-carboxylate (Pyr2C). May be required to degrade trans-3-hydroxy-L-proline from the diet and originating from the degradation of proteins such as collagen-IV that contain it. Belongs to the proline racemase family.Protein type: Isomerase; EC 4.2.1.77Chromosomal Location of Human Ortholog: 14q23.1Molecular Function: hydro-lyase activity; proline racemase activity; trans-L-3-hydroxyproline dehydratase activityBiological Process: metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96EM0 |
| NCBI GenInfo Identifier: | 21389361 |
| NCBI Gene ID: | 112849 |
| NCBI Accession: | NP_653182.1 |
| UniProt Secondary Accession: | Q96EM0,Q96LJ5 |
| UniProt Related Accession: | Q96EM0 |
| Molecular Weight: | 38,138 Da |
| NCBI Full Name: | trans-3-hydroxy-L-proline dehydratase |
| NCBI Synonym Full Names: | L-3-hydroxyproline dehydratase (trans-) |
| NCBI Official Symbol: | L3HYPDH |
| NCBI Official Synonym Symbols: | C14orf149 |
| NCBI Protein Information: | trans-3-hydroxy-L-proline dehydratase |
| UniProt Protein Name: | Trans-3-hydroxy-L-proline dehydratase |
| UniProt Synonym Protein Names: | Trans-L-3-hydroxyproline dehydratase |
| Protein Family: | Trans-L-3-hydroxyproline dehydratase |
| UniProt Gene Name: | L3HYPDH |
| UniProt Entry Name: | T3HPD_HUMAN |
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