L1 Antibody (PACO32588)
- SKU:
- PACO32588
- Product Type:
- Antibody
- Reactivity:
- Virus
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | L1 Antibody (PACO32588) |
| Antibody SKU: | PACO32588 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human papillomavirus type 16 |
| Immunogen: | Recombinant Human papillomavirus type 16 Major capsid protein L1 protein (6-471AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2. |
| Synonyms: | Major capsid protein L1, L1 |
| UniProt Protein Function: | Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P03101 |
| NCBI GenInfo Identifier: | 978128213 |
| NCBI Gene ID: | |
| NCBI Accession: | P03101.3 |
| UniProt Secondary Accession: | P03101,O00530 |
| UniProt Related Accession: | P03101 |
| Molecular Weight: | 56,278 Da |
| NCBI Full Name: | Major capsid protein L1 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Major capsid protein L1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Packaging protein |
| UniProt Gene Name: | L1 |
| UniProt Entry Name: |
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