Description
Product Name: | KYNU Monoclonal Antibody |
Product Code: | CAB23962 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC62786 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | HeLa, A-549, Mouse liver, Mouse kidney, Rat liver |
Cellular Location: | Cytoplasm, cytosol |
Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-465 of human KYNU (NP_003928.1). |
Sequence: | MEPSS LELPA DTVQR IAAEL KCHPT DERVA LHLDE EDKLR HFREC FYIPK IQDLP PVDLS LVNKD ENAIY FLGNS LGLQP KMVKT YLEEE LDKWA KIAAY GHEVG KRPWI TGDES IVGLM KDIVG ANEKE IALMN ALTVN LHLLM LSFFK PTPKR YKILL EAKAF PSDHY AIESQ LQLHG LNIEE SMRMI KPREG EETLR IEDIL EVIEK EGDSI AVILF SGVHF YTGQH FNIPA ITKAG QAKGC YVGFD LAHAV GNVEL YLHDW GVDFA CWCSY KYLNA GAGGI AGAFI HEKHA HTIKP ALVGW FGHEL STRFK MDNKL QLIPG VCGFR ISNPP ILLVC SLHAS LEIFK QATMK ALRKK SVLLT GYLEY LIKHN YGKDK AATKK PVVNI ITPSH VEERG CQLTI TFSVP NKDVF QELEK RGVVC DKRNP NGIRV APVPL YNSFH DVYKF TNLLT SILDS AETKN |
Synonyms: | KYNU, KYNUU, kynureninase |
Calculated MW: | 34kDa/52kDa |
Observed MW: | 52kDa |