Name: KRTAP3-2 Antibody (PACO41014)
SKU: PACO41014
Availability: OutOfStock

Antibody Name:	KRTAP3-2 Antibody (PACO41014)
Antibody SKU:	PACO41014
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:	Human
Immunogen:	Recombinant Human Keratin-associated protein 3-2 protein (2-98AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Immunohistochemistry of paraffin-embedded human skin tissue using PACO41014 at dilution of 1:100.

Background:

In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

Synonyms:

Keratin-associated protein 3-2 (High sulfur keratin-associated protein 3.2) (Keratin-associated protein 3.2), KRTAP3-2, KAP3.2 KRTAP3.2

UniProt Protein Function:	KRTAP3-2: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. Belongs to the KRTAP type 3 family.Chromosomal Location of Human Ortholog: 17q21.2Molecular Function: protein binding
UniProt Protein Details:
NCBI Summary:	This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008]
UniProt Code:	Q9BYR7
NCBI GenInfo Identifier:	21961309
NCBI Gene ID:	83897
NCBI Accession:	BC034582
UniProt Secondary Accession:	Q9BYR7
UniProt Related Accession:	Q9BYR7
Molecular Weight:	10,407 Da
NCBI Full Name:	Homo sapiens keratin associated protein 3-2, mRNA
NCBI Synonym Full Names:	keratin associated protein 3-2
NCBI Official Symbol:	KRTAP3-2
NCBI Official Synonym Symbols:	KAP3.2; KRTAP3.2
NCBI Protein Information:	keratin-associated protein 3-2
UniProt Protein Name:	Keratin-associated protein 3-2
UniProt Synonym Protein Names:	High sulfur keratin-associated protein 3.2; Keratin-associated protein 3.2
Protein Family:
UniProt Gene Name:	KRTAP3-2
UniProt Entry Name:	KRA32_HUMAN