Description
| Antibody Name: | KRTAP13-1 Antibody (PACO37806) |
| Antibody SKU: | PACO37806 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Keratin-associated protein 13-1 protein (1-172AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. |
| Synonyms: | Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1), KRTAP13-1, KAP13.1 KRTAP13.1 |
| UniProt Protein Function: | KRTAP13-1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. Belongs to the PMG family.Chromosomal Location of Human Ortholog: 21q22.1Cellular Component: intermediate filament |
| UniProt Protein Details: | |
| NCBI Summary: | Hair keratins and hair keratin-associated proteins (KAPs), such as KRTAP13-1, are the main structural proteins of hair fibers (Rogers et al., 2002 [PubMed 12359730]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8IUC0 |
| NCBI GenInfo Identifier: | 109288006 |
| NCBI Gene ID: | 140258 |
| NCBI Accession: | NP_853630.2 |
| UniProt Secondary Accession: | Q8IUC0,Q14D20, Q3LI79 |
| UniProt Related Accession: | Q8IUC0 |
| Molecular Weight: | 18,320 Da |
| NCBI Full Name: | keratin-associated protein 13-1 |
| NCBI Synonym Full Names: | keratin associated protein 13-1 |
| NCBI Official Symbol: | KRTAP13-1 |
| NCBI Official Synonym Symbols: | KAP13.1; KRTAP13.1 |
| NCBI Protein Information: | keratin-associated protein 13-1 |
| UniProt Protein Name: | Keratin-associated protein 13-1 |
| UniProt Synonym Protein Names: | High sulfur keratin-associated protein 13.1 |
| Protein Family: | Keratin-associated protein |
| UniProt Gene Name: | KRTAP13-1 |
| UniProt Entry Name: | KR131_HUMAN |