Description
| Antibody Name: | KRTAP11-1 Antibody (PACO37654) |
| Antibody SKU: | PACO37654 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Keratin-associated protein 11-1 protein (1-186AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. |
| Synonyms: | Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1), KRTAP11-1, KAP11.1 KRTAP11.1 |
| UniProt Protein Function: | KRTAP11-1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. Belongs to the PMG family.Chromosomal Location of Human Ortholog: 21q22.1Cellular Component: keratin filamentMolecular Function: structural molecule activity |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8IUC1 |
| NCBI GenInfo Identifier: | 28466985 |
| NCBI Gene ID: | 337880 |
| NCBI Accession: | NP_787054.1 |
| UniProt Secondary Accession: | Q8IUC1,A1L4I8 |
| UniProt Related Accession: | Q8IUC1 |
| Molecular Weight: | 17 kDa (MW of target protein) |
| NCBI Full Name: | keratin-associated protein 11-1 |
| NCBI Synonym Full Names: | keratin associated protein 11-1 |
| NCBI Official Symbol: | KRTAP11-1 |
| NCBI Official Synonym Symbols: | HACL1; HACL-1; KAP11.1 |
| NCBI Protein Information: | keratin-associated protein 11-1 |
| UniProt Protein Name: | Keratin-associated protein 11-1 |
| UniProt Synonym Protein Names: | High sulfur keratin-associated protein 11.1 |
| Protein Family: | |
| UniProt Gene Name: | KRTAP11-1 |
| UniProt Entry Name: | KR111_HUMAN |