Description
system_update_alt Datasheet
Product Name: | KRT8 Antibody |
Product Sku: | CPAB0577 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human KRT8 mAb, clone PAT3D11A, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human KRT8 protein purified from Ecoli. |
Clone: | PAT3D11A. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA |
Purification Method: | |
Isotype: | IgG3 |
Background: | Cytokeratin 8 (KRT8) belongs to the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. KRT8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. KRT8 has a role in retaining cellular structural integrity and also functions in signal transduction and cellular differentiation. KRT8 gene mutations cause cryptogenic cirrhosis. |
Synonyms: | Keratin type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, KRT8, CYK8, KO, CK8, K2C8, CARD2. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |