Krt18 Antibody (PACO60745)

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SKU:
PACO60745
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
Applications:
WB
Applications:
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated

Description

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Antibody Name:Krt18 Antibody (PACO60745)
Antibody SKU:PACO60745
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200
Species Reactivity:Mouse, Human
Immunogen:Recombinant Mouse Keratin, type I cytoskeletal 18 protein (200-423AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageWestern Blot. Positive WB detected in: Hela whole cell lysate, Mouse kidney tissue, Mouse liver tissue. All lanes: Krt18 antibody at 5.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 48 kDa. Observed band size: 48 kDa.
Product ImageIHC image of PACO60745 diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Product ImageIHC image of PACO60745 diluted at 1:100 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
Synonyms:Keratin, type I cytoskeletal 18 (Cytokeratin endo B) (Keratin D) (Cytokeratin-18) (CK-18) (Keratin-18) (K18), Krt18, Kerd Krt1-18
UniProt Protein Function:When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
UniProt Code:P05784
NCBI GenInfo Identifier:254540068
NCBI Gene ID:16668
NCBI Accession:NP_034794.2
UniProt Related Accession:P05784
Molecular Weight:43; 48kDa
NCBI Full Name:keratin, type I cytoskeletal 18
NCBI Synonym Full Names:keratin 18
NCBI Official Symbol:Krt18  
NCBI Official Synonym Symbols:K18; CK18; Krt1-18  
NCBI Protein Information:keratin, type I cytoskeletal 18
UniProt Protein Name:Keratin, type I cytoskeletal 18
UniProt Synonym Protein Names:Cytokeratin endo B; Keratin D; Cytokeratin-18; CK-18; Keratin-18; K18
UniProt Gene Name:Krt18  
ELISA Kits
Mouse Krt18 ELISA Kit
Mouse Keratin, type I cytoskeletal 18 (Krt18) ELISA Kit
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
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