KRAS Monoclonal Antibody
- SKU:
- CAB23382
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | KRAS Monoclonal Antibody |
| Product Code: | CAB23382 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC59916 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, C2C12, C6 |
| Cellular Location: | Cell membrane, Cytoplasm, Cytoplasmic side, Lipid-anchor, Cytosol |
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-188 of human KRAS (NP_203524.1). |
| Sequence: | MTEYK LVVVG AGGVG KSALT IQLIQ NHFVD EYDPT IEDSY RKQVV IDGET CLLDI LDTAG QEEYS AMRDQ YMRTG EGFLC VFAIN NTKSF EDIHH YREQI KRVKD SEDVP MVLVG NKCDL PSRTV DTKQA QDLAR SYGIP FIETS AKTRQ RVEDA FYTLV REIRQ YRLKK ISKEE KTPGC VKIKK CII |
| Synonyms: | NS, NS3, OES, CFC2, RALD, K-Ras, KRAS1, KRAS2, RASK2, KI-RAS, C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, K-Ras 2, 'C-K-RAS, c-Ki-ras, c-Ki-ras2 |
| Calculated MW: | 22kDa |
| Observed MW: | 21kDa |
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