KRAS+HRAS+NRAS Monoclonal Antibody
- SKU:
- CAB22438
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
- Applications:
- IP
Description
| Product Name: | KRAS+HRAS+NRAS Monoclonal Antibody |
| Product Code: | CAB22438 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC2656 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, IP, ELISA |
| Key Applications: | Western blotting, Immunofluorescence, Immunoprecipitation |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200, IP 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, MCF7, Mouse lung, Mouse brain, Rat lung, Rat brain |
| Cellular Location: | Cytosol, Extracellular exosome, Golgi apparatus, Plasma membrane |
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Ras (P01111). |
| Sequence: | MTEYK LVVVG AGGVG KSALT IQLIQ NHFVD EYDPT IEDSY RKQVV IDGET CLLDI LDTAG QEEYS AMRDQ YMRTG EGFLC VFAIN NSKSF ADINL YREQI |
| Synonyms: | C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RALD, RASK2, c-Ki-ras2 |
| Calculated MW: | 21kDa |
| Observed MW: | 21kDa |
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