KLRF1 Antibody (PACO19915)
- SKU:
- PACO19915
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | KLRF1 Antibody (PACO19915) |
| Antibody SKU: | PACO19915 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human KLRF1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19915(KLRF1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO19915(KLRF1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release |
| Synonyms: | killer cell lectin-like receptor subfamily F, member 1 |
| UniProt Protein Function: | KLRF1: Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Receptor, misc.; Membrane protein, integralChromosomal Location of Human Ortholog: 12p13.31Cellular Component: membrane; integral to plasma membraneMolecular Function: transmembrane receptor activity; MHC class I receptor activity; carbohydrate bindingBiological Process: cell surface receptor linked signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009] |
| UniProt Code: | Q9NZS2 |
| NCBI GenInfo Identifier: | 625180299 |
| NCBI Gene ID: | 51348 |
| NCBI Accession: | NP_001278751.1 |
| UniProt Secondary Accession: | Q9NZS2,Q4KMT5, Q96PR2, Q96PR3, Q9NZS1 |
| UniProt Related Accession: | Q9NZS2 |
| Molecular Weight: | 27kDa |
| NCBI Full Name: | killer cell lectin-like receptor subfamily F member 1 isoform KLRF1-s |
| NCBI Synonym Full Names: | killer cell lectin-like receptor subfamily F, member 1 |
| NCBI Official Symbol: | KLRF1 |
| NCBI Official Synonym Symbols: | NKp80; CLEC5C |
| NCBI Protein Information: | killer cell lectin-like receptor subfamily F member 1 |
| UniProt Protein Name: | Killer cell lectin-like receptor subfamily F member 1 |
| UniProt Synonym Protein Names: | Activating coreceptor NKp80; C-type lectin domain family 5 member C |
| Protein Family: | Killer cell lectin-like receptor subfamily |
| UniProt Gene Name: | KLRF1 |
| UniProt Entry Name: | KLRF1_HUMAN |
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