Description
| Antibody Name: | Klkb1 Antibody (PACO27825) |
| Antibody SKU: | PACO27825 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Rat |
| Immunogen: | Recombinant Rat Plasma kallikrein protein (391-638AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. |
| Synonyms: | Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain], Klkb1, Klk3 Pk |
| UniProt Protein Function: | The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. |
| NCBI Summary: | serine protease that plays a role in blood coagulation [RGD, Feb 2006] |
| UniProt Code: | P14272 |
| NCBI GenInfo Identifier: | 125186 |
| NCBI Gene ID: | 25048 |
| NCBI Accession: | P14272.1 |
| UniProt Related Accession: | P14272 |
| Molecular Weight: | 71,274 Da |
| NCBI Full Name: | Plasma kallikrein |
| NCBI Synonym Full Names: | kallikrein B1 |
| NCBI Official Symbol: | Klkb1 |
| NCBI Official Synonym Symbols: | PK; Klk3; Kalp1; KALP15 |
| NCBI Protein Information: | plasma kallikrein |
| UniProt Protein Name: | Plasma kallikrein |
| UniProt Synonym Protein Names: | Fletcher factor; Kininogenin; Plasma prekallikrein |
| Protein Family: | Plasma kallikrein |
| UniProt Gene Name: | Klkb1 |