KLF4 Polyclonal Antibody

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SKU:
CAB21709
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:KLF4 Polyclonal Antibody
Product Code:CAB21709
Reactivity:Human
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location:Nucleus

This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 180-479 of human KLF4 (NP_004226.3).
Sequence:PPTAP FNLAD INDVS PSGGF VAELL RPELD PVYIP PQQPQ PPGGG LMGKF VLKAS LSAPG SEYGS PSVIS VSKGS PDGSH PVVVA PYNGG PPRTC PKIKQ EAVSS CTHLG AGPPL SNGHR PAAHD FPLGR QLPSR TTPTL GLEEV LSSRD CHPAL PLPPG FHPHP GPNYP SFLPD QMQPQ VPPLH YQELM PPGSC MPEEP KPKRG RRSWP RKRTA THTCD YAGCG KTYTK SSHLK AHLRT HTGEK PYHCD WDGCG WKFAR SDELT RHYRK HTGHR PFQCQ KCDRA FSRSD HLALH MKRHF
Synonyms:EZF, GKLF
Calculated MW:55kDa
Observed MW:Refer to figures
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