Description
| Product Name: | KLF1 Polyclonal Antibody |
| Product Code: | CAB24503 |
| Reactivity: | Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Rat liver |
| Cellular Location: | Nucleus |
This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 211-311 of human KLF1 (NP_006554.1). |
| Sequence: | QYQGH FQLFR GLQGP APGPA TSPSF LSCLG PGTVG TGLGG TAEDP GVIAE TAPSK RGRRS WARKR QAAHT CAHPG CGKSY TKSSH LKAHL RTHTG EKPYA C |
| Synonyms: | KLF1, EKLF, CDAN4, HBFQTL6, INLU, Kruppel like factor 1 |
| Calculated MW: | 38kDa |
| Observed MW: | 38kDa |