KIR2DS4 Monoclonal Antibody [P5F2AT] (CPAB0510)
![KIR2DS4 Monoclonal Antibody [P5F2AT] (CPAB0510)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58731/63913/kir2ds4-monoclonal-antibody-p5f2at-cpab0510__65753__41856.1706535198.jpg?c=1 "KIR2DS4 Monoclonal Antibody [P5F2AT] (CPAB0510)")
- SKU:
- CPAB0510
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- P5F2AT
- Applications:
- WB
- Applications:
- ELISA
![KIR2DS4 Monoclonal Antibody [P5F2AT] (CPAB0510)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58731/63913/kir2ds4-monoclonal-antibody-p5f2at-cpab0510__65753__41856.1706535198.jpg?c=1&imbypass=on "KIR2DS4 Monoclonal Antibody [P5F2AT] (CPAB0510)")
Description
system_update_alt Datasheet
| Product Name: | KIR2DS4 Antibody |
| Product Sku: | CPAB0510 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human KIR2DS4 mAb is derived from hybridization of mouse SP2/ myeloma cells with spleen cells from BALB/c mice immunized with recombinant human KIR2DS4 purified from Ecoli. |
| Clone: | P5F2AT. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, ELISA |
| Purification Method: | KIR2DS4 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG2b |
| Background: | Killer-cell immunoglobulin-like receptors (KIRs), are a family of cell surface glycoproteins found on Natural Killer (NK) Cells, which are important cells of the immune system. They control the killing function of these cells by interacting with MHC class I molecules, which are expressed on all cell types. This interaction allows them to identify virally infected cells or tumor cells that have a distinctive low level of Class I MHC on their surface. The majority of KIRs are inhibitory, which means that their recognition of MHC suppresses the cytotoxic activity of their NK cell. Only a limited number of KIRs have the capacity to activate cells. The KIR genes are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). KIR molecules are extremely polymorphic, meaning their gene sequences differ significantly between individuals, so that different individuals have different arrays/repertoires of KIR genes. |
| Synonyms: | Killer cell immunoglobulin-like receptor 2DS4, MHC class I NK cell receptor, Natural killer-associated transcript 8, NKAT-8, P58 natural killer cell receptor clone CL-39, p58 NK receptor, CL-17, CD158 antigen-like family member I, CD158i antigen, KIR2DS4, CD158I, KKA3, NKAT8, KIR1D, KIR412, MGC120019, MGC125315, MGC125317. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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