KIF26B Antibody (PACO35838)
- SKU:
- PACO35838
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | KIF26B Antibody (PACO35838) |
| Antibody SKU: | PACO35838 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Kinesin-like protein KIF26B protein (8-133AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human breast cancer using PACO35838 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human gastric cancer using PACO35838 at dilution of 1:100. |
| Background: | Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction. Although it seems to lack ATPase activity it is constitutively associated with microtubules. |
| Synonyms: | Kinesin-like protein KIF26B, KIF26B |
| UniProt Protein Function: | KIF26B: Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction. Belongs to the kinesin-like protein family. KIF26 subfamily. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Motor; Microtubule-bindingChromosomal Location of Human Ortholog: 1q44Cellular Component: cytoplasm; kinesin complex; microtubuleMolecular Function: ATP binding; microtubule binding; plus-end-directed microtubule motor activityBiological Process: axon guidance; cytoskeleton-dependent intracellular transport; establishment of cell polarity; metabolic process; microtubule-based movement; positive regulation of cell-cell adhesion; protein localization |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q2KJY2 |
| NCBI GenInfo Identifier: | 124430752 |
| NCBI Gene ID: | 55083 |
| NCBI Accession: | NP_060482.2 |
| UniProt Secondary Accession: | Q2KJY2,Q6ZQR9, Q6ZUZ0, Q8IUN3, Q8IVR1, Q9NWB4 |
| UniProt Related Accession: | Q2KJY2 |
| Molecular Weight: | 184,420 Da |
| NCBI Full Name: | kinesin-like protein KIF26B |
| NCBI Synonym Full Names: | kinesin family member 26B |
| NCBI Official Symbol: | KIF26B |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | kinesin-like protein KIF26B |
| UniProt Protein Name: | Kinesin-like protein KIF26B |
| UniProt Synonym Protein Names: | |
| Protein Family: | Kinesin-like protein |
| UniProt Gene Name: | KIF26B |
| UniProt Entry Name: | KI26B_HUMAN |
| Antibodies |
| KIF26B Antibody (PACO10100) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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