KIF25 Antibody (PACO63903)
- SKU:
- PACO63903
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | KIF25 Antibody (PACO63903) |
| Antibody SKU: | PACO63903 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Kinesin-like protein KIF25 protein (1-262AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO63903 diluted at 1:100 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Minus-end microtubule-dependent motor protein (By similarity). Acts as a negative regulator of centrosome separation required to prevent premature centrosome separation during interphase. Required to maintain a centered nucleus to ensure that the spindle is stably oriented at the onset of mitosis. May also act as a negative regulator of amino acid, starvation-induced autophagy. |
| Synonyms: | Kinesin-like protein KIF25 (Kinesin-like protein 3), KIF25, KNSL3 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a member of the kinesin-like protein family. Protein family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. However, the particular function of this gene product has not yet been determined. Two alternatively spliced transcript variants which encode products have been described. Other splice variants have been found that lack exon 2 and the initiation codon for translation. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UIL4 |
| NCBI GenInfo Identifier: | 154124879 |
| NCBI Gene ID: | 3834 |
| NCBI Accession: | NP_085118 |
| UniProt Secondary Accession: | Q9UIL4 |
| UniProt Related Accession: | Q9UIL4 |
| Molecular Weight: | 41kDa |
| NCBI Full Name: | kinesin-like protein KIF25 isoform 1 |
| NCBI Synonym Full Names: | kinesin family member 25 |
| NCBI Official Symbol: | KIF25 |
| NCBI Official Synonym Symbols: | KNSL3 |
| NCBI Protein Information: | kinesin-like protein KIF25 |
| UniProt Protein Name: | Kinesin-like protein KIF25 |
| UniProt Synonym Protein Names: | Kinesin-like protein 3 |
| Protein Family: | Kinesin-like protein |
| UniProt Gene Name: | KIF25 |
| UniProt Entry Name: | KIF25_HUMAN |
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