KIF24 Antibody (PACO36366)
- SKU:
- PACO36366
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | KIF24 Antibody (PACO36366) |
| Antibody SKU: | PACO36366 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Kinesin-like protein KIF24 protein (1168-1368AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human melanoma using PACO36366 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human heart tissue using PACO36366 at dilution of 1:100. |
| Background: | Microtubule-dependent motor protein that acts as a negative regulator of ciliogenesis by mediating recruitment of CCP110 to mother centriole in cycling cells, leading to restrict nucleation of cilia at centrioles. Mediates depolymerization of microtubules of centriolar origin, possibly to suppress aberrant cilia formation. |
| Synonyms: | Kinesin-like protein KIF24, KIF24, C9orf48 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the kinesin superfamily of microtubule-based motor proteins which are involved in the intracellular transport of membranous organelles, protein complexes, and mRNAs. They also play critical roles in mitosis, morphogenesis, and signal transduction. The encoded protein contains an N-terminal sterile alpha motif (SAM) domain and an ATP-binding kinesin motor domain. It binds centriolar coiled coil protein 110 and centrosomal protein 97 and localizes to the mother centriole to regulate ciliogenesis by controlling microtubule polymerization. [provided by RefSeq, Mar 2017] |
| UniProt Code: | Q5T7B8 |
| NCBI GenInfo Identifier: | 154426306 |
| NCBI Gene ID: | 347240 |
| NCBI Accession: | NP_919289 |
| UniProt Secondary Accession: | Q5T7B8 |
| UniProt Related Accession: | Q5T7B8 |
| Molecular Weight: | 151kDa |
| NCBI Full Name: | kinesin-like protein KIF24 |
| NCBI Synonym Full Names: | kinesin family member 24 |
| NCBI Official Symbol: | KIF24 |
| NCBI Official Synonym Symbols: | C9orf48; bA571F15.4 |
| NCBI Protein Information: | kinesin-like protein KIF24 |
| UniProt Protein Name: | Kinesin-like protein KIF24 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Kinesin-like protein |
| UniProt Gene Name: | KIF24 |
| UniProt Entry Name: | KIF24_HUMAN |
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