Description
Product Name: | KIF12 Polyclonal Antibody |
Product Code: | CAB8780 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Cellular Location: | Cytoplasm, cytoskeleton |
This gene encodes a member of the kinesin superfamily of microtubule-associated molecular motors with functions related to the microtubule cytosekelton. Members of this superfamily play important roles in intracellular transport and cell division. A similar protein in mouse functions in the beta cell antioxidant signaling cascade, acting as a scaffold for the transcription factor specificity protein 1 (Sp1). Mice that lack this gene exhibit beta cell oxidative stress resulting in hypoinsulinemic glucose intolerance.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 284-513 of human KIF12 (NP_612433.1). |
Sequence: | NLYGM LQEFM LENER LRKEK SQLQN SRDLA QNEQR ILAQQ VHALE RRLLS ACYHH QQGPG LTPPC PCLMA PAPPC HALPP LYSCP CCHIC PLCRV PLAHW ACLPG EHHLP QVLDP EASGG RPPSA RPPPW APPCS PGSAK CPRER SHSDW TQTRV LAEML TEEEV VPSAP PLPVR PPKTS PGLRG GAGVP NLAQR LEALR DQIGS SLRRG RSQPP CSEGA RSPGQ VLPPH |
Synonyms: | PFIC8 |
Calculated MW: | 71kDa |
Observed MW: | Refer to figures |